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silicolife

silicolife



Location:Portugal
 
Description:SilicoLife is a new company devoted to create computational solutions for the fast growing Industrial Biotechnology market. It benefits from the expertise and international exposure of the team in the fields of Bioinformatics and Systems Biology, to provide highly specialized services, in an area most of the times absent in biotech companies.

SilicoLife is devoted to accelerate strain and bioprocess optimization in Industrial Biotechnology by the use of proprietary computational and modelling tools.

SilicoLife provides dedicated models, robust algorithms and user-friendly software tools to accelerate strain design and bioprocess optimization, therefore accelerating R&D efforts and shortening the time to market of new biotechnology-based products.

For a great variety of microorganisms and products, SilicoLife can offer ready-to-use solutions in the form of molecular targets that optimize yield and productivities or dedicated user-friendly software tools to be internally adopted by the companies to achieve their own results.
 
Keywords:bioinformatics, systems biology
 
Work experience:Simão Soares - Chief Executive Officer
Simão Soares is an Informatics Engineer and has a M.Sc. in Bioinformatics. He did part of his M.Sc. work at the Center for Microbial Biotechnology, Technical University of Denmark. He is the company CEO and the bridge between the company and its principal collaborators.

Miguel Rocha - Chief Technology Officer
Miguel Rocha is a faculty member at the Department of Informatics in the University of Minho and a researcher in the CCTC research center. He has a PhD in Computer Science and his main research on the last few years has been devoted to Bioinformatics and Systems Biology, with a special focus on the development of methods for the modeling and optimization of biological processes.

Isabel Rocha - Chief Scientific Officer
Isabel Rocha is an Assistant Professor at the University of Minho, Portugal. Her international collaborations include a joint project with the multi-national chemicals and health care company Dupont and the participation in the European Commission funded Coordination Action SYSINBIO. She is the PI of several projects in Systems Biology applied to Industrial Biotechnology and Life Sciences, with more than 40 papers published in international journals, books and international conferences.


Other members: Several collaborators, both Ph.D. students and former M.Sc. students, complement the above-mentioned team. This multidisciplinary team includes people from the Life Sciences, Computer Science and Bioinformatics.
 
Years of experience:5
 
Highlights:Relevant publications and websites of the SilicoLife Team:
* OptFlux; Software Platform for Metabolic Engineering - www.optflux.org
* OptFlux: an open-source software platform for in silico metabolic engineering. BMC Systems Biology 4:45, 2010.
* Natural computation meta-heuristics for the in silico optimization of microbial strains. BMC Bioinformatics 9, 499, 2008.
* Metabolic Network Topology Reveals Transcriptional Regulatory Signatures of Type 2 Diabetes. PLoS Computational Biology, 6(4),2010.
 


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